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  1. 4-1-communicable-diseases-disease-prevention-and-the-immune-system
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  2. 4-2-biodiversity
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  3. 4-3-classification-and-evolution
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  4. 5-1-communication-and-homeostasis
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  5. 5-2-excretion
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  6. 5-3-neuronal-communication
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  7. 5-4-hormonal-communication
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  8. 5-5-plant-and-animal-responses
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  9. 5-6-photosynthesis
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  10. 5-7-respiration
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  11. 6-1-cellular-control
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  12. 6-2-patterns-of-inheritance
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  13. 6-3-manipulating-genomes
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  14. 6-4-cloning-and-biotechnology
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  15. 6-5-ecosystems
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  16. 6-6-populations-and-sustainability
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  17. 1-1-practical-skills-written-assessment
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  18. 1-2-practical-skills-endorsement-assessment
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  19. 2-1-cell-structure
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  20. 2-2-biological-molecules
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  21. 2-3-nucleotides-and-nucleic-acids
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  22. 2-4-enzymes
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  23. 2-5-biological-membranes
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  24. 2-6-cell-division-cell-diversity-and-cellular-organisation
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  25. 3-1-exchange-surfaces
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  26. 3-2-transport-in-animals
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  27. 3-3-transport-in-plants
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The Human Brain

  • The brain, alongside the spinal cord, is part of our central nervous system (CNS)

  • The brain is made of billions of interconnected neurones and is responsible for controlling complex behaviours

  • Within the brain are different regions that carry out different functions

  • These regions include:

    • The cerebrum

    • The hypothalamus

    • The pituitary gland

    • The cerebellum

    • The medulla oblongata

The-Brain-Structure, downloadable AS & A Level Biology revision notes

The regions of the human brain

The cerebrum

  • Largest part of the brain in humans (accounts for about 80% of the total mass of the brain)

  • Carries out a large variety of functions involved with conscious activities, including:

    • Vision

    • Hearing

    • Speech

    • Thinking

    • Memory

  • Consists of five lobes

  • Divided into two halves, known as the cerebral hemispheres

    • The hemispheres are joined together by a band of nerve fibres, known as the corpus callosum

    • The right hemisphere controls the left side of the body and the left one controls the right side

  • Has a thin outer layer known as the cerebral cortex or ‘grey matter

    • The cerebral cortex consists of the cell bodies of neurones

    • It is highly folded, which increases its surface area and allows it to contain a greater number of neurones

    • With more neurones in the brain, more connections between neurones can be made

    • This is important, as the more connections between neurones in the brain, the greater the ability of the brain to carry out more complex behaviours

  • Beneath the cerebral cortex or grey matter layer is the ‘white matter’

    • The white matter consists of the myelinated axons of neurones

Brain cross-section, downloadable AS & A Level Biology revision notes

A cross-section of the brain showing regions found within the cerebrum.

The hypothalamus

  • Area in the middle of the lower part of the brain

  • It is found just above the pituitary gland (which it is connected to)

  • Monitors the blood as it is flowing through it and in response, releases hormones (involved in homeostasis) itself or stimulates the pituitary gland to release certain hormones

  • Main functions include:

    • Regulating body temperature – by monitoring blood temperature and initiating a homeostatic response if this temperature gets too high or too low

    • Osmoregulation – by monitoring how concentrated the blood is and if it gets too concentrated, stimulating the posterior pituitary gland to release anti-diuretic hormone (ADH), which causes increased water retention in the kidneys. The hypothalamus also generates a feeling of thirst, causing us to increase our water intake

    • Regulating digestive activity – controls the secretion of enzymes in the gut and peristalsis. The hypothalamus also generates a feeling of hunger, causing us to increase our food intake if blood nutrient concentrations get too low

    • Controlling endocrine functions – the hypothalamus releases chemicals that cause the pituitary gland to release certain hormones that control a variety of processes (e.g. metabolism, growth and development, puberty sexual functions, sleep, mood)

The pituitary gland

  • At the bottom of the brain, below the hypothalamus

  • Produces a range of hormones

    • Some of these directly influence and regulate processes in the body but some stimulate the release of further hormones from specific, remote locations in the body (e.g. from other glands)

  • Divided into two sections: the anterior pituitary and posterior pituitary

    • Anterior pituitary – produces and releases certain hormones

    • Posterior pituitary – stores and releases hormones produced by the hypothalamus (e.g. ADH and oxytocin)

The cerebellum

  • Lies below the cerebrum

  • Controls motor coordination

    • This includes balance

    • Balance is a highly complex function that requires coordination between multiple parts, including the eyes, semicircular canals in the ears, and many muscles

  • Functions only subconsciously (i.e. all of the actions it controls are involuntary)

The medulla oblongata

  • Also known as the medulla

  • Found at the very base of the brain, where it joins the spinal cord

  • Contains three ‘centres’ that control different functions:

    • The cardiac centre – controls heart rate

    • The vasomotor centre – controls blood pressure by controlling the contraction of smooth muscles in arteriole walls

    • The respiratory centre – controls breathing rate (contains an inspiratory centre and an expiratory centre)