Biology_Alevel_Ocr
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4-1-communicable-diseases-disease-prevention-and-the-immune-system16 主题
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4-1-1-common-pathogens-and-communicable-diseases
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4-1-2-transmission-of-communicable-pathogens
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4-1-3-plant-defences-against-pathogens
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4-1-4-non-specific-immune-responses
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4-1-5-phagocytes
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4-1-6-blood-cells
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4-1-7-the-t-lymphocyte-response
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4-1-8-the-b-lymphocyte-response
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4-1-9-primary-and-secondary-immune-responses
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4-1-10-antibodies
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4-1-11-opsonins-agglutinins-and-anti-toxins
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4-1-12-types-of-immunity
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4-1-13-autoimmune-diseases
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4-1-14-principles-of-vaccination
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4-1-15-sources-of-medicine
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4-1-16-antibiotics
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4-1-1-common-pathogens-and-communicable-diseases
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4-2-biodiversity10 主题
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4-2-1-biodiversity
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4-2-2-sampling-to-determine-biodiversity
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4-2-3-practical-investigating-biodiversity-using-sampling
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4-2-4-measuring-species-richness-and-species-evenness
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4-2-5-simpsons-index
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4-2-6-genetic-diversity
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4-2-7-factors-affecting-biodiversity
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4-2-8-reasons-for-maintaining-biodiversity
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4-2-9-methods-of-maintaining-biodiversity
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4-2-10-conservation-agreements
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4-2-1-biodiversity
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4-3-classification-and-evolution15 主题
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4-3-1-classification-of-species
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4-3-2-binomial-system
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4-3-3-classification-of-the-three-domains
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4-3-4-classification-of-the-five-kingdoms
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4-3-5-classification-and-phylogeny
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4-3-6-evidence-of-evolution
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4-3-7-types-of-variation
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4-3-8-standard-deviation
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4-3-9-variation-t-test-method
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4-3-10-variation-t-test-worked-example
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4-3-11-spearmans-rank-correlation
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4-3-12-adaptation
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4-3-13-natural-selection
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4-3-14-evolution-of-resistance
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4-3-15-consequences-of-resistance
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4-3-1-classification-of-species
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5-1-communication-and-homeostasis4 主题
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5-2-excretion10 主题
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5-2-1-the-importance-of-excretion
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5-2-2-the-mammalian-liver-structure
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5-2-3-the-mammalian-liver-function
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5-2-4-the-liver-under-the-microscope
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5-2-5-the-mammalian-kidney-structure
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5-2-6-the-mammalian-kidney-function
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5-2-7-the-kidney-under-the-microscope
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5-2-8-osmoregulation
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5-2-9-kidney-failure
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5-2-10-excretory-products-and-medical-diagnosis
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5-2-1-the-importance-of-excretion
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5-3-neuronal-communication9 主题
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5-4-hormonal-communication4 主题
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5-5-plant-and-animal-responses16 主题
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5-5-1-plant-responses
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5-5-2-investigating-phototropism-and-geotropism
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5-5-3-plant-hormones
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5-5-4-auxins-and-apical-dominance
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5-5-5-gibberellin
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5-5-6-practical-effect-of-plant-hormones-on-growth
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5-5-7-commercial-use-of-plant-hormones
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5-5-8-mammalian-nervous-system
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5-5-9-the-human-brain
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5-5-10-reflex-actions
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5-5-11-coordination-of-responses
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5-5-12-factors-affecting-heart-rate
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5-5-13-investigating-factors-affecting-heart-rate
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5-5-14-mammalian-muscle-structure
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5-5-15-transmission-across-a-neuromuscular-junction
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5-5-16-the-sliding-filament-model
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5-5-1-plant-responses
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5-6-photosynthesis10 主题
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5-6-1-photosynthesis-and-respiration
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5-6-2-chloroplast-structure-and-function
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5-6-3-photosynthetic-pigments
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5-6-4-practical-investigating-photosynthetic-pigments-with-chromatography
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5-6-5-the-light-dependent-stage
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5-6-6-using-the-products-of-the-light-dependent-reaction
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5-6-7-the-light-independent-stage
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5-6-8-uses-of-triose-phosphate
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5-6-9-factors-affecting-the-rate-of-photosynthesis
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5-6-10-practical-investigating-factors-affecting-the-rate-of-photosynthesis
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5-6-1-photosynthesis-and-respiration
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5-7-respiration14 主题
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5-7-14-practical-respirometer
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5-7-1-the-need-for-cellular-respiration
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5-7-2-structure-of-the-mitochondrion
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5-7-3-the-four-stages-in-aerobic-respiration
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5-7-4-glycolysis
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5-7-5-the-link-reaction
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5-7-6-the-krebs-cycle
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5-7-7-the-role-of-coenzymes
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5-7-8-oxidative-phosphorylation
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5-7-9-anaerobic-respiration
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5-7-10-energy-yield-of-aerobic-vs-anaerobic-respiration
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5-7-11-practical-investigating-the-rate-of-respiration
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5-7-12-respiratory-substrates
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5-7-13-respiratory-quotient-rq
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5-7-14-practical-respirometer
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6-1-cellular-control7 主题
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6-2-patterns-of-inheritance13 主题
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6-2-1-key-terms-in-genetics
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6-2-2-variation-phenotype
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6-2-3-variation-sexual-reproduction
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6-2-4-predicting-inheritance-monohybrid-crosses
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6-2-5-predicting-inheritance-dihybrid-crosses
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6-2-6-predicting-inheritance-identifying-linkage
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6-2-7-predicting-inheritance-identifying-epistasis
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6-2-8-predicting-inheritance-chi-squared-test
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6-2-9-continuous-and-discontinuous-variation
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6-2-10-factors-affecting-evolution
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6-2-11-the-hardy-weinberg-principle
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6-2-12-isolation-and-speciation
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6-2-13-artificial-selection
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6-2-1-key-terms-in-genetics
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6-3-manipulating-genomes11 主题
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6-3-1-dna-sequencing
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6-3-2-comparing-genomes
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6-3-3-non-coding-dna-and-regulatory-genes
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6-3-4-synthetic-biology
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6-3-5-polymerase-chain-reaction
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6-3-6-electrophoresis
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6-3-7-dna-profiling
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6-3-8-genetic-engineering
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6-3-9-genetic-engineering-techniques
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6-3-10-uses-of-genetic-engineering
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6-3-11-gene-therapy
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6-3-1-dna-sequencing
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6-4-cloning-and-biotechnology14 主题
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6-4-1-natural-clones-in-plants
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6-4-2-producing-cuttings
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6-4-3-production-of-artificial-clones-in-plants
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6-4-4-uses-of-plant-cloning
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6-4-5-natural-clones-in-animals
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6-4-6-production-of-artificial-clones-in-animals
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6-4-7-uses-of-animal-cloning
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6-4-8-microorganisms-and-biotechnology
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6-4-9-microorganisms-and-food-production
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6-4-10-culturing-microorganisms
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6-4-11-batch-and-continuous-fermentation
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6-4-12-standard-growth-curve-of-microorganisms
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6-4-13-factors-affecting-the-growth-of-microorganisms
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6-4-14-immobilised-enzymes-in-biotechnology
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6-4-1-natural-clones-in-plants
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6-5-ecosystems7 主题
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6-6-populations-and-sustainability6 主题
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1-1-practical-skills-written-assessment7 主题
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1-2-practical-skills-endorsement-assessment16 主题
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1-2-1-practical-ethical-use-of-organisms
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1-2-2-practical-aseptic-techniques
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1-2-3-practical-dissection-of-gas-exchange-surfaces-in-fish-and-insects
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1-2-4-drawing-cells-from-blood-smears
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1-2-5-practical-investigating-biodiversity-using-sampling
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1-2-6-practical-data-loggers-and-computer-modelling
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1-2-7-practical-investigating-the-rate-of-diffusion
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1-2-8-practical-investigating-water-potential
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1-2-9-practical-factors-affecting-membrane-structure-and-permeability
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1-2-10-biochemical-tests-reducing-sugars-and-starch
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1-2-11-biochemical-tests-lipids
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1-2-12-biochemical-tests-proteins
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1-2-13-chromatography
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1-2-14-serial-dilutions
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1-2-15-practical-investigating-the-rate-of-transpiration
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1-2-16-practical-using-a-light-microscope
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1-2-1-practical-ethical-use-of-organisms
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2-1-cell-structure9 主题
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2-2-biological-molecules17 主题
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2-2-1-properties-of-water
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2-2-2-monomers-and-polymers
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2-2-3-monosaccharides
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2-2-4-the-glycosidic-bond
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2-2-5-polysaccharides
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2-2-6-biochemical-tests-reducing-sugars-and-starch
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2-2-7-lipids-and-ester-bonds
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2-2-8-lipids-structure-and-function
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2-2-9-biochemical-tests-lipids
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2-2-10-amino-acids-and-peptide-bonds
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2-2-11-protein-structure
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2-2-12-globular-proteins
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2-2-13-fibrous-proteins
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2-2-14-inorganic-ions
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2-2-15-biochemical-tests-proteins
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2-2-16-finding-the-concentration-of-a-substance
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2-2-17-chromatography
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2-2-1-properties-of-water
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2-3-nucleotides-and-nucleic-acids8 主题
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2-4-enzymes9 主题
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2-4-1-the-role-of-enzymes
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2-4-2-enzyme-action
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2-4-3-enzyme-activity-ph
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2-4-4-enzyme-activity-temperature
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2-4-5-enzyme-activity-enzyme-concentration
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2-4-6-enzyme-activity-substrate-concentration
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2-4-7-enzyme-activity-enzyme-inhibitors
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2-4-8-coenzymes-cofactors-and-prosthetic-groups
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2-4-9-practical-measuring-enzyme-activity
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2-4-1-the-role-of-enzymes
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2-5-biological-membranes9 主题
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2-5-1-the-cell-surface-membrane
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2-5-2-membrane-structure-and-permeability
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2-5-3-diffusion-and-facilitated-diffusion
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2-5-4-practical-investigating-the-rate-of-diffusion
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2-5-5-active-transport
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2-5-6-endocytosis-and-exocytosis
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2-5-7-osmosis
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2-5-8-osmosis-in-animal-and-plant-cells
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2-5-9-practical-investigating-water-potential
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2-5-1-the-cell-surface-membrane
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2-6-cell-division-cell-diversity-and-cellular-organisation11 主题
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2-6-1-the-cell-cycle
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2-6-2-the-stages-of-mitosis
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2-6-3-identifying-mitosis-in-plant-cells
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2-6-4-the-significance-of-mitosis
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2-6-5-the-stages-of-meiosis
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2-6-6-the-significance-of-meiosis
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2-6-7-specialised-cells
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2-6-8-the-organisation-of-cells
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2-6-9-stem-cells
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2-6-10-stem-cells-in-animals-and-plants
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2-6-11-the-use-of-stem-cells
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2-6-1-the-cell-cycle
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3-1-exchange-surfaces7 主题
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3-2-transport-in-animals12 主题
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3-2-1-the-need-for-transport-systems-in-animals
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3-2-2-circulatory-systems
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3-2-3-blood-vessels
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3-2-4-tissue-fluid
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3-2-5-the-mammalian-heart
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3-2-6-practical-mammalian-heart-dissection
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3-2-7-the-cardiac-cycle
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3-2-8-cardiac-output
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3-2-9-heart-action-initiation-and-control
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3-2-10-electrocardiograms-ecgs
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3-2-11-the-role-of-haemoglobin
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3-2-12-adult-and-fetal-haemoglobin
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3-2-1-the-need-for-transport-systems-in-animals
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3-3-transport-in-plants11 主题
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3-3-1-the-need-for-transport-systems-in-plants
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3-3-2-the-xylem-and-phloem
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3-3-3-the-xylem
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3-3-4-the-phloem
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3-3-5-transverse-sections-stems-roots-and-leaves
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3-3-6-the-process-of-transpiration
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3-3-7-transpiration-in-plants
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3-3-8-practical-investigating-the-rate-of-transpiration
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3-3-9-translocation
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3-3-10-the-mass-flow-hypothesis
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3-3-11-the-adaptations-of-xerophytic-and-hydrophytic-plants
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3-3-1-the-need-for-transport-systems-in-plants
5-5-13-investigating-factors-affecting-heart-rate
Investigating Factors Affecting Heart Rate
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There are a wide range of factors that influence the heart rate of an organism
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Experiments can be designed to investigate the effect of a named variable on an organism’s heart rate
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These experiments are commonly done using humans
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Serious care needs to be taken during these experiments to ensure that no test subjects are harmed
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Some of the factors that can influence heart rate include:
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Drugs
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Caffeine
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Alcohol
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Sex
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Weight
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Height
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Temperature
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Diet
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Dehydration
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When designing experiments investigating a single factor, it is essential to try and control the other variables
Investigating the effect of caffeine on the heart rate of humans
Apparatus
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Heart rate monitor
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Caffeine solution of a known concentration
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Measuring cylinders
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Cups
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One group of healthy humans
Method
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Use the heart rate monitor to record the heart rates of each individual while at rest
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These results can be used to calculate the mean heart rate of the group as well as the range of resting heart rates for the group prior to caffeine consumption
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Use the measuring cylinder to pour 200ml of the caffeine solution into a cup (one for each individual)
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Ask each individual to consume the drink
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Wait 15 minutes
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Use the heart rate monitor to record the heart rates of each individual while at rest
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These results can be used to calculate the mean heart rate of the group as well as the range of resting heart rates for the group after caffeine consumption
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It is important that the individuals taking part are not moving and all sat down so that these variables are controlled
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Repeat the heart rate measurements every 15 minutes for 2 hours
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This will show the duration for which caffeine has an effect on the heart rate
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Present the results in a graph or table form
Limitations
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Care needs to be taken when selecting the caffeine concentration
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Too much caffeine can be dangerous, while too little may show no effect
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It is very difficult to ensure that individuals within a sample group are sufficiently similar
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By using the same group for the before and after measurements this is not as much of an issue
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If multiple groups were used, with some consuming caffeine and some not, then this would be a major issue and care would need to be taken to find individuals with a similar life history (same sex, age, weight and height etc.)
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Examiner Tips and Tricks
Exams may ask about the safety and ethical considerations when studying the heart rates of humans. An experiment should be designed so that the safety of any of the subjects is never at risk, for example they should not be pushed to exercise at such an intensity that could cause a heart attack.