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  1. 4-1-communicable-diseases-disease-prevention-and-the-immune-system
    16 主题
  2. 4-2-biodiversity
    10 主题
  3. 4-3-classification-and-evolution
    15 主题
  4. 5-1-communication-and-homeostasis
    4 主题
  5. 5-2-excretion
    10 主题
  6. 5-3-neuronal-communication
    9 主题
  7. 5-4-hormonal-communication
    4 主题
  8. 5-5-plant-and-animal-responses
    16 主题
  9. 5-6-photosynthesis
    10 主题
  10. 5-7-respiration
    14 主题
  11. 6-1-cellular-control
    7 主题
  12. 6-2-patterns-of-inheritance
    13 主题
  13. 6-3-manipulating-genomes
    11 主题
  14. 6-4-cloning-and-biotechnology
    14 主题
  15. 6-5-ecosystems
    7 主题
  16. 6-6-populations-and-sustainability
    6 主题
  17. 1-1-practical-skills-written-assessment
    7 主题
  18. 1-2-practical-skills-endorsement-assessment
    16 主题
  19. 2-1-cell-structure
    9 主题
  20. 2-2-biological-molecules
    17 主题
  21. 2-3-nucleotides-and-nucleic-acids
    8 主题
  22. 2-4-enzymes
    9 主题
  23. 2-5-biological-membranes
    9 主题
  24. 2-6-cell-division-cell-diversity-and-cellular-organisation
    11 主题
  25. 3-1-exchange-surfaces
    7 主题
  26. 3-2-transport-in-animals
    12 主题
  27. 3-3-transport-in-plants
    11 主题
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Stem cells in the bone marrow

  • Examples of distinct types of differentiated cell that arise from a common stem cell within bone marrow include:

    • erythrocytes

    • neutrophils

  • Stem cells in bone marrow are multipotent adult stem cells

Erythrocytes

  • Erythrocytes are red blood cells, specialised to aid oxygen transport around the body

  • Red blood cells lack a nucleus so they cannot perform mitosis to give rise to new cells; this means that new erythrocytes develop from bone marrow stem cells in order to maintain the red blood cell count in the blood

  • The process by which erythrocytes arise from stem cells includes changes such as:

    • loss of the nucleus

    • a shape change to form a biconcave disc

    • increased production of haemoglobin protein

    • an increase in membrane flexibility

Erythropoiesis 1, downloadable AS & A Level Biology revision notes
Erythropoiesis 2, downloadable AS & A Level Biology revision notes

Stem cells in bone marrow differentiate to give rise to erythrocytes

Neutrophils

  • The same stem cells that form erythrocytes also give rise to neutrophils, a type of white blood cell that is specialised to destroy pathogens by phagocytosis

  • Changes that occur as stem cells differentiate into neutrophils include:

    • indentations form in the nucleus, giving it a lobed structure

    • production of hydrolytic enzymes increases

    • lysosomes that contain hydrolytic enzymes accumulate

    • membrane flexibility increases

Meristems

  • Plant stem cells are found in regions where growth is taking place; these tissues are known as meristems

  • Examples of distinct types of differentiated cell that arise from a common stem cell within plant meristems include:

    • xylem

    • phloem

  • The specialised cells that make up xylem and phloem are located in a meristem known as cambium

  • Cambium cells are found between regions of xylem and phloem tissue in plant stems and roots

Cambium meristem, downloadable AS & A Level Biology revision notes

The cells that make up xylem and phloem tissue arise from the same type of stem cell within a meristem known as cambium

Xylem and phloem

  • Xylem cells are specialised to allow the transport of water and minerals; changes that occur when cambium cells differentiate into xylem cells include:

    • the deposition of lignin in cell walls

    • loss of cytoplasm

    • loss of end walls

  • Phloem tissue is specialised to allow the transport of assimilates; changes that allow cambium cells to differentiate into phloem sieve tubes include:

    • a reduction in cytoplasm volume

    • loss of some organelles

    • end walls develop into sieve plates