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  1. 1-biological-molecules

    1-1-biological-molecules-carbohydrates
    11 主题
  2. 1-2-biological-molecules-lipids
    3 主题
  3. 1-3-biological-molecules-proteins
    5 主题
  4. 1-4-proteins-enzymes
    12 主题
  5. 1-5-nucleic-acids-structure-and-dna-replication
    8 主题
  6. 1-6-atp-water-and-inorganic-ions
    4 主题
  7. 2-cell-structure
    2-1-cell-structure
    7 主题
  8. 2-2-the-microscope-in-cell-studies
    4 主题
  9. 2-3-cell-division-in-eukaryotic-and-prokaryotic-cells
    8 主题
  10. 2-4-cell-membranes-and-transport
    7 主题
  11. 2-5-cell-recognition-and-the-immune-system
    7 主题
  12. 2-6-vaccines-disease-and-monoclonal-antibodies
    6 主题
  13. 3-exchange-and-transport
    3-1-adaptations-for-gas-exchange
    6 主题
  14. 3-2-human-gas-exchange
    10 主题
  15. 3-3-digestion-and-absorption
    5 主题
  16. 3-4-mass-transport-in-animals
    6 主题
  17. 3-5-the-circulatory-system-in-animals
    8 主题
  18. 3-6-mass-transport-in-plants
    6 主题
  19. 4-genetics-variation-and-interdependence
    4-1-dna-genes-and-chromosomes
    7 主题
  20. 4-2-dna-and-protein-synthesis
    6 主题
  21. 4-3-genetic-diversity-mutations-and-meiosis
    7 主题
  22. 4-4-genetic-diversity-and-adaptation
    6 主题
  23. 4-5-species-and-taxonomy
    4 主题
  24. 4-6-biodiversity
    9 主题
  25. 5-energy-transfers-in-and-between-organisms-a-level-only
    5-1-photosynthesis-a-level-only
    5 主题
  26. 5-2-respiration-a-level-only
    7 主题
  27. 5-3-energy-and-ecosystems-a-level-only
    9 主题
  28. 5-4-nutrient-cycles-a-level-only
    4 主题
  29. 6-organisms-respond-to-changes-in-their-environments-a-level-only
    6-1-response-to-stimuli-a-level-only
    12 主题
  30. 6-2-nervous-coordination-a-level-only
    10 主题
  31. 6-3-skeletal-muscles-a-level-only
    6 主题
  32. 6-4-homeostasis-a-level-only
    11 主题
  33. 7-genetics-populations-evolution-and-ecosystems-a-level-only
    7-1-inheritance-a-level-only
    6 主题
  34. 7-2-populations-a-level-only
    3 主题
  35. 7-3-evolution-a-level-only
    5 主题
  36. 7-4-populations-in-ecosystems-a-level-only
    7 主题
  37. 8-the-control-of-gene-expression-a-level-only
    8-1-genetic-mutations-a-level-only
    2 主题
  38. 8-2-regulation-of-gene-expression-a-level-only
    11 主题
  39. 8-3-using-genome-projects-a-level-only
    4 主题
  40. 8-4-gene-technologies-a-level-only
    13 主题
  41. exam-guidance-and-skills
    essay-guidance
    3 主题
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The role of adrenaline

  • The hormone adrenaline can increase blood glucose concentration as follows:

    • it binds to receptors on the cell surface membranes of target cells

    • it activates enzymes that convert glycogen to glucose

The second messenger model of adrenaline action

  • The mechanism by which adrenaline activates enzymes is the same as that seen in glucagon

    1. Adrenaline binds to receptors on the membrane of liver cells

    2. Adenylate cyclase is activated

    3. Adenylate cyclase catalyses the conversion of ATP to the second messenger, cyclic AMP (cAMP)

    4. cAMP activates protein kinase A

    5. Protein kinase A initiates a cascade of reactions that results in the activation of enzymes that break down glycogen to glucose

Diagram showing the adrenaline pathway: adrenaline binds to a receptor, activating adenylyl cyclase, converting ATP to cAMP, triggering glycogen to glucose conversion.
Adrenaline activates enzymes that break down glycogen via the second messenger model of hormone action

Examiner Tips and Tricks

The specification covers the second messenger model in the context of glucagon and adrenaline, but you should be prepared to answer questions that require you to apply your understanding of this model to unfamiliar contexts.