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  1. 1-biological-molecules

    1-1-biological-molecules-carbohydrates
    11 主题
  2. 1-2-biological-molecules-lipids
    3 主题
  3. 1-3-biological-molecules-proteins
    5 主题
  4. 1-4-proteins-enzymes
    12 主题
  5. 1-5-nucleic-acids-structure-and-dna-replication
    8 主题
  6. 1-6-atp-water-and-inorganic-ions
    4 主题
  7. 2-cell-structure
    2-1-cell-structure
    7 主题
  8. 2-2-the-microscope-in-cell-studies
    4 主题
  9. 2-3-cell-division-in-eukaryotic-and-prokaryotic-cells
    8 主题
  10. 2-4-cell-membranes-and-transport
    7 主题
  11. 2-5-cell-recognition-and-the-immune-system
    7 主题
  12. 2-6-vaccines-disease-and-monoclonal-antibodies
    6 主题
  13. 3-exchange-and-transport
    3-1-adaptations-for-gas-exchange
    6 主题
  14. 3-2-human-gas-exchange
    10 主题
  15. 3-3-digestion-and-absorption
    5 主题
  16. 3-4-mass-transport-in-animals
    6 主题
  17. 3-5-the-circulatory-system-in-animals
    8 主题
  18. 3-6-mass-transport-in-plants
    6 主题
  19. 4-genetics-variation-and-interdependence
    4-1-dna-genes-and-chromosomes
    7 主题
  20. 4-2-dna-and-protein-synthesis
    6 主题
  21. 4-3-genetic-diversity-mutations-and-meiosis
    7 主题
  22. 4-4-genetic-diversity-and-adaptation
    6 主题
  23. 4-5-species-and-taxonomy
    4 主题
  24. 4-6-biodiversity
    9 主题
  25. 5-energy-transfers-in-and-between-organisms-a-level-only
    5-1-photosynthesis-a-level-only
    5 主题
  26. 5-2-respiration-a-level-only
    7 主题
  27. 5-3-energy-and-ecosystems-a-level-only
    9 主题
  28. 5-4-nutrient-cycles-a-level-only
    4 主题
  29. 6-organisms-respond-to-changes-in-their-environments-a-level-only
    6-1-response-to-stimuli-a-level-only
    12 主题
  30. 6-2-nervous-coordination-a-level-only
    10 主题
  31. 6-3-skeletal-muscles-a-level-only
    6 主题
  32. 6-4-homeostasis-a-level-only
    11 主题
  33. 7-genetics-populations-evolution-and-ecosystems-a-level-only
    7-1-inheritance-a-level-only
    6 主题
  34. 7-2-populations-a-level-only
    3 主题
  35. 7-3-evolution-a-level-only
    5 主题
  36. 7-4-populations-in-ecosystems-a-level-only
    7 主题
  37. 8-the-control-of-gene-expression-a-level-only
    8-1-genetic-mutations-a-level-only
    2 主题
  38. 8-2-regulation-of-gene-expression-a-level-only
    11 主题
  39. 8-3-using-genome-projects-a-level-only
    4 主题
  40. 8-4-gene-technologies-a-level-only
    13 主题
  41. exam-guidance-and-skills
    essay-guidance
    3 主题
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The human retina

  • The eye is a sense organ containing receptors that are sensitive to:

    • light intensity

    • light wavelength

  • Light receptors are located in the retina, a layer of cells at the back of the eye; the retina contains:

    • rod cells

      • sensitive to light intensity only

      • distributed across the entire retina

    • cone cells

      • sensitive to different wavelengths of visible light

      • concentrated in the fovea

  • Rods and cones detect light as follows:

    1. light causes the chemical breakdown of optical pigments inside rods and cones

    2. the breakdown of these optical pigments results in a generator potential

    3. if the generator potential is large enough then a nerve impulse is sent along a bipolar neurone to the optic nerve

  • Information is relayed to the brain via the optic nerve

Diagram of the human eye with labelled parts including sclera, cornea, iris, pupil, lens, retina, optic nerve, fovea, and ciliary muscle.
The eye focuses light onto the retina at the back of the eye

Examiner Tips and Tricks

Note that you do not need to learn the details of eye structure; this has been included here for context.

Sensitivity to light and wavelength

  • Rod and cone cells differ in their sensitivity to light and wavelength

  • Rod cells are:

    • very sensitive to light

      • Multiple rod cells connect to a single bipolar cell, meaning that many weak generator potentials together can trigger a nerve impulse in the bipolar cell

        • This is an example of spatial summation

    • not sensitive to wavelength

  • Cone cells are

    • less sensitive to light

      • Each cone cell connects to its own bipolar neurone, so the generator potential from an individual cone cell must be higher than in a rod cell to trigger a nerve impulse in the bipolar cell

    • sensitive to different wavelengths of light

      • When red-sensitive, blue-sensitive and green-sensitive cones cells are stimulated in different numbers and locations, colour images are generated

Diagram of retinal structure showing rod and cone cells, bipolar neurones, ganglion cells, and impulse direction towards the optic nerve.
Many rod cells connect to a single bipolar neurone, allowing summation and resulting in high sensitivity to light, while cone cells connect individually to bipolar neurones and so are less sensitive to light

Visual acuity

  • Visual acuity is:

the ability to distinguish between two separate points when viewing an image

  • The higher the visual acuity, the more detailed an image will be

  • Rod cells have low visual acuity

    • As described above, multiple rod cells synapse with a single bipolar cell

    • Information from many neighbouring rod cells is detected as a single point when the brain generates an image

      • The brain is not able to determine which impulses have been generated by which specific rod cell

  • Cone cells have high visual acuity

    • A single cone cell synapses with a single bipolar cell, allowing each cell to send a separate impulse to the brain

    • Information from each individual cone cell will be interpreted as separate points when the brain generates an image

Diagram showing how cone stimulation affects light perception: A) 1 cone, 1 spot perceived; B) 2 cones, 2 spots perceived; C) 2 cones, 1 spot perceived.
Each cone cell produces its own impulse when stimulated, allowing the brain to generate detailed images

Examiner Tips and Tricks

Remember that, due to the type of connection that each cell type forms with its bipolar neurones, and the types of pigment contained:

  • rod cells:

    • are highly sensitive to light

    • can only generate black and white images

    • provide low visual acuity

  • cone cells:

    • are less sensitive to light

    • can generate coloured images

    • provide high visual acuity

You should be prepared to apply this knowledge in exam questions, e.g. to explain how the distribution of rods and cones affects vision in different parts of the retina.