Biology AS OCR
-
1-1-practical-skills-written-assessment AS7 主题
-
1-2-practical-skills-endorsement-assessment AS16 主题
-
1-2-1-practical-ethical-use-of-organisms as
-
1-2-2-practical-aseptic-techniques as
-
1-2-3-practical-dissection-of-gas-exchange-surfaces-in-fish-and-insects as
-
1-2-4-drawing-cells-from-blood-smears as
-
1-2-5-practical-investigating-biodiversity-using-sampling as
-
1-2-6-practical-data-loggers-and-computer-modelling as
-
1-2-7-practical-investigating-the-rate-of-diffusion as
-
1-2-8-practical-investigating-water-potential as
-
1-2-9-practical-factors-affecting-membrane-structure-and-permeability as
-
1-2-10-biochemical-tests-reducing-sugars-and-starch as
-
1-2-11-biochemical-tests-lipids as
-
1-2-12-biochemical-tests-proteins as
-
1-2-13-chromatography as
-
1-2-14-serial-dilutions as
-
1-2-15-practical-investigating-the-rate-of-transpiration as
-
1-2-16-practical-using-a-light-microscope as
-
1-2-1-practical-ethical-use-of-organisms as
-
2-1-cell-structure AS9 主题
-
2-1-2-using-a-microscope as
-
2-1-3-drawing-cells as
-
2-1-4-magnification-and-resolution as
-
2-1-5-eukaryotic-cells as
-
2-1-6-eukaryotic-cells-under-the-microscope as
-
2-1-7-organelles-and-the-production-of-proteins as
-
2-1-8-the-cytoskeleton as
-
2-1-9-prokaryotic-and-eukaryotic-cells as
-
2-1-1-studying-cells as
-
2-1-2-using-a-microscope as
-
2-2-biological-molecules AS17 主题
-
2-2-1-properties-of-water as
-
2-2-2-monomers-and-polymers as
-
2-2-3-monosaccharides as
-
2-2-4-the-glycosidic-bond as
-
2-2-5-polysaccharides as
-
2-2-6-biochemical-tests-reducing-sugars-and-starch as
-
2-2-7-lipids-and-ester-bonds as
-
2-2-8-lipids-structure-and-function as
-
2-2-9-biochemical-tests-lipids as
-
2-2-10-amino-acids-and-peptide-bonds as
-
2-2-11-protein-structure as
-
2-2-12-globular-proteins as
-
2-2-13-fibrous-proteins as
-
2-2-14-inorganic-ions as
-
2-2-15-biochemical-tests-proteins as
-
2-2-16-finding-the-concentration-of-a-substance as
-
2-2-17-chromatography as
-
2-2-1-properties-of-water as
-
2-3-nucleotides-and-nucleic-acids AS8 主题
-
2-4-enzymes AS9 主题
-
2-4-1-the-role-of-enzymes as
-
2-4-2-enzyme-action as
-
2-4-3-enzyme-activity-ph as
-
2-4-4-enzyme-activity-temperature as
-
2-4-5-enzyme-activity-enzyme-concentration as
-
2-4-6-enzyme-activity-substrate-concentration as
-
2-4-7-enzyme-activity-enzyme-inhibitors as
-
2-4-8-coenzymes-cofactors-and-prosthetic-groups as
-
2-4-9-practical-measuring-enzyme-activity as
-
2-4-1-the-role-of-enzymes as
-
2-5-biological-membranes AS9 主题
-
2-5-1-the-cell-surface-membrane as
-
2-5-2-membrane-structure-and-permeability as
-
2-5-3-diffusion-and-facilitated-diffusion as
-
2-5-4-practical-investigating-the-rate-of-diffusion as
-
2-5-5-active-transport as
-
2-5-6-endocytosis-and-exocytosis as
-
2-5-7-osmosis as
-
2-5-8-osmosis-in-animal-and-plant-cells as
-
2-5-9-practical-investigating-water-potential as
-
2-5-1-the-cell-surface-membrane as
-
2-6-cell-division-cell-diversity-and-cellular-organisation AS11 主题
-
2-6-1-the-cell-cycle as
-
2-6-2-the-stages-of-mitosis as
-
2-6-3-identifying-mitosis-in-plant-cells as
-
2-6-4-the-significance-of-mitosis as
-
2-6-5-the-stages-of-meiosis as
-
2-6-6-the-significance-of-meiosis as
-
2-6-7-specialised-cells as
-
2-6-8-the-organisation-of-cells as
-
2-6-9-stem-cells as
-
2-6-10-stem-cells-in-animals-and-plants as
-
2-6-11-the-use-of-stem-cells as
-
2-6-1-the-cell-cycle as
-
3-1-exchange-surfaces AS7 主题
-
3-2-transport-in-animals AS12 主题
-
3-2-1-the-need-for-transport-systems-in-animals as
-
3-2-2-circulatory-systems as
-
3-2-3-blood-vessels as
-
3-2-4-tissue-fluid as
-
3-2-5-the-mammalian-heart as
-
3-2-6-practical-mammalian-heart-dissection as
-
3-2-7-the-cardiac-cycle as
-
3-2-8-cardiac-output as
-
3-2-9-heart-action-initiation-and-control as
-
3-2-10-electrocardiograms-ecgs as
-
3-2-11-the-role-of-haemoglobin as
-
3-2-12-adult-and-fetal-haemoglobin as
-
3-2-1-the-need-for-transport-systems-in-animals as
-
3-3-transport-in-plants AS11 主题
-
3-3-1-the-need-for-transport-systems-in-plants as
-
3-3-2-the-xylem-and-phloem as
-
3-3-3-the-xylem as
-
3-3-4-the-phloem as
-
3-3-5-transverse-sections-stems-roots-and-leaves as
-
3-3-6-the-process-of-transpiration as
-
3-3-7-transpiration-in-plants as
-
3-3-8-practical-investigating-the-rate-of-transpiration as
-
3-3-9-translocation as
-
3-3-10-the-mass-flow-hypothesis as
-
3-3-11-the-adaptations-of-xerophytic-and-hydrophytic-plants as
-
3-3-1-the-need-for-transport-systems-in-plants as
-
4-1-communicable-diseases-disease-prevention-and-the-immune-system AS16 主题
-
4-1-1-common-pathogens-and-communicable-diseases as
-
4-1-2-transmission-of-communicable-pathogens as
-
4-1-3-plant-defences-against-pathogens as
-
4-1-4-non-specific-immune-responses as
-
4-1-5-phagocytes as
-
4-1-6-blood-cells as
-
4-1-7-the-t-lymphocyte-response as
-
4-1-8-the-b-lymphocyte-response as
-
4-1-9-primary-and-secondary-immune-responses as
-
4-1-10-antibodies as
-
4-1-11-opsonins-agglutinins-and-anti-toxins as
-
4-1-12-types-of-immunity as
-
4-1-13-autoimmune-diseases as
-
4-1-14-principles-of-vaccination as
-
4-1-15-sources-of-medicine as
-
4-1-16-antibiotics as
-
4-1-1-common-pathogens-and-communicable-diseases as
-
4-2-biodiversity AS10 主题
-
4-2-1-biodiversity as
-
4-2-2-sampling-to-determine-biodiversity as
-
4-2-3-practical-investigating-biodiversity-using-sampling as
-
4-2-4-measuring-species-richness-and-species-evenness as
-
4-2-5-simpsons-index as
-
4-2-6-genetic-diversity as
-
4-2-7-factors-affecting-biodiversity as
-
4-2-8-reasons-for-maintaining-biodiversity as
-
4-2-9-methods-of-maintaining-biodiversity as
-
4-2-10-conservation-agreements as
-
4-2-1-biodiversity as
-
4-3-classification-and-evolution AS15 主题
-
4-3-1-classification-of-species as
-
4-3-2-binomial-system as
-
4-3-3-classification-of-the-three-domains as
-
4-3-4-classification-of-the-five-kingdoms as
-
4-3-5-classification-and-phylogeny as
-
4-3-6-evidence-of-evolution as
-
4-3-7-types-of-variation as
-
4-3-8-standard-deviation as
-
4-3-9-variation-t-test-method as
-
4-3-10-variation-t-test-worked-example as
-
4-3-11-spearmans-rank-correlation as
-
4-3-12-adaptation as
-
4-3-13-natural-selection as
-
4-3-14-evolution-of-resistance as
-
4-3-15-consequences-of-resistance as
-
4-3-1-classification-of-species as
4-3-13-natural-selection as
Exam code:H020
Effects of Natural Selection
Genetic variation
-
Organisms of the same species have very similar genomes, but two individuals (even twins) will have differences between their DNA base sequences
-
These differences in DNA base sequences between individual organisms within a species population are called genetic variation
-
Genetic variation is transferred from one generation to the next and results in genetic diversity within a species
Effects of genetic variation
-
There needs to be some level of genetic diversity within a population for natural selection to occur
-
Differences in the alleles possessed by individuals within a population result in differences in phenotypes
-
Some phenotypes may be advantageous, disadvantageous or neutral, compared to other phenotypes
-
-
Selection pressures increase the chance of individuals with a specific (more advantageous) phenotype surviving and reproducing over others
-
The individuals with the favoured phenotypes are described as having a higher fitness
-
The fitness of an organism is defined as its ability to survive and pass on its alleles to offspring
-
Organisms with higher fitness possess adaptations that make them better suited to their environment
-
-
A population with a large gene pool or high genetic diversity has a strong ability to adapt to change
-
If a population has a small gene pool or very low genetic diversity then they are much less able to adapt to changes in the environment and so can become vulnerable to extinction
-
Cheetahs are an example of a species with a small gene pool
-
They experienced a very large decline in numbers approximately 10,000 years ago
-
This left small, fragmented populations of individuals remaining
-
There was no mixing between populations and large amounts of inbreeding occurred
-
This is problematic for conservation as low genetic variation means the species are less likely to be able to respond (survive) in the event of any environmental changes
-
Environmental factors
-
Environmental factors affect the chance of survival of an organism – they act as a selection pressure
-
Every individual within a species population has the potential to reproduce and have offspring which contribute to population growth
-
If all the offspring of every individual survived to adulthood and reproduced, the population would experience exponential growth
-
This type of growth only happens when there are no environmental factors or population checks acting on the population (for example, when there are plentiful resources and no disease)
-
One well known but rare example of exponential growth in a population is the introduction of 24 European rabbits into Australia in the 1800s. The rabbits had an abundance of resources, little or no competition and no natural predators. This meant the population increased rapidly and they became a major pest
-
In reality, there are several environmental factors that prevent every individual in a population making it to adulthood and reproducing
-

Exponential growth in a population of rabbits that have no environmental checks
Natural selection
-
The main processes resulting in natural selection are as follows:
-
Random mutation can produce new alleles of a gene
-
Many mutations are harmful or neutral but, under certain environmental conditions, the new alleles may benefit their possessor, leading to an increased chance of survival and increased reproductive success
-
The advantageous allele is passed onto the next generation
-
As a result, over several generations, the new allele will increase in frequency in the population
-
Example of natural selection in rabbits
-
Variation in fur colour exists within rabbit populations
-
At a single gene locus, normal brown fur is produced by a dominant allele whereas white fur is produced by a recessive allele in a homozygous individual
-
Rabbits have natural predators like foxes which act as a selection pressure
-
Rabbits with a white coat do not camouflage as well as rabbits with brown fur, meaning predators are more likely to see white rabbits when hunting
-
As a result, rabbits with white fur are less likely to survive than rabbits with brown fur
-
Therefore, the rabbits with brown fur have a selection advantage, so they are more likely to survive to reproductive age and be able to pass on their alleles to their offspring
-
Over many generations, the frequency of alleles for brown fur will increase and the frequency of alleles for white fur will decrease

Selective pressures acting on a rabbit population for one generation. Predation by foxes causes the frequency of brown fur alleles in rabbits to increase and the frequency of white fur alleles in rabbits to decrease.
Examiner Tips and Tricks
Exams often ask questions about how the process of natural selection occurs for a certain species. The principles of natural selection described above are always the same! You just need to edit the details to make them specific to the question:
-
Within a species, there is always variation and chance mutation
-
Some individuals will develop a phenotype (characteristic) that gives them a survival advantage and this allows them to:
-
live longer
-
breed more
-
be more likely to pass their genes on
-
-
Repeated over generations, the ‘mutated’ phenotype will become the norm
-
If genetic differences accumulate and the population is isolated then a new species may evolve
Remember, it is the concept you have to understand, not a specific example. You will be expected to use unfamiliar information to explain how selection produces changes within a population of a species and interpret data relating to the effect of selection in producing change within populations.
Responses