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Biology AS Edexcel Snab Revision

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Exam code:8BN0

Treatment of CVD

  • While reducing the risk factors and lowering the risk of developing cardiovascular disease (CVD) is the best option, CVD is still very common and treatment options are needed

  • There are a number of different treatment options for cardiovascular disease, many of which involve taking medication

  • Types of medication for the treatment of CVD include

    • Antihypertensives

    • Statins

    • Anticoagulants

    • Platelet inhibitors

Antihypertensives

  • These drugs work by lowering blood pressure

    • High blood pressure is also known as hypertension

  • Lowering blood pressure reduces the risk of arterial endothelial damage and therefore reduces the risk of atheromas and thrombosis

  • Beta blockers, vasodilators and diuretics act as antihypertensives

    • Beta blockers prevent increases in heart rate

    • Vasodilators increase the diameter of the blood vessels

    • Diuretics reduce blood volume by decreasing the amount of sodium reabsorbed into the blood by the kidneys, therefore decreasing the volume of water reabsorbed into the blood 

Statins

  • These drugs work by lowering blood cholesterol 

    • They block an enzyme in the liver which is needed to make cholesterol

  • This lowers the LDL concentration in the blood therefore reducing the risk of atheroma formation

    • LDLs are sometimes known as ‘bad’ cholesterol; at high levels they increase the risk of atheromas forming

Anticoagulants

  • These drugs reduce blood clotting

    • Blood clotting can be referred to as blood coagulation

  • Reduced formation of blood clots decreases the likelihood of thrombosis and therefore reduces the risk of blood vessels being blocked by blood clots

Platelet inhibitors

  • These are also substances which reduce blood clotting

    • Platelet inhibitors are a type of anticoagulant

  • They prevent the clumping together of platelets, so preventing the formation of blood clots

  • Aspirin is an example of a platelet inhibitor

Benefits and Risks of Cardiovascular Disease Drugs Table

benefits-and-risks-of-cardiovascular-disease-drugs-table

Examiner Tips and Tricks

You need to know these four examples and their associated benefits and risks. Be sure to be specific on how each medication type prevents CVD.

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