Biology AS Edexcel Snab Revision
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lifestyle-health-and-risk as19 主题
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diet-and-health interpreting-data-on-risk-factors
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diet-and-health treatment-of-cvd
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diet-and-health energy-budgets-and-diet
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diet-and-health monosaccharides
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diet-and-health the-glycosidic-bond
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diet-and-health disaccharides
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diet-and-health polysaccharides
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diet-and-health lipids-and-ester-bonds
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diet-and-health reducing-risk-factors-of-cvd
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diet-and-health practical-vitamin-c-content
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the-circulatory-system the-need-for-a-circulatory-system
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the-circulatory-system the-importance-of-water-in-transport
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the-circulatory-system mammalian-heart-structure-and-function
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the-circulatory-system blood-vessels-structure-and-function
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the-circulatory-system cardiac-cycle
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the-circulatory-system investigating-heart-rate
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the-circulatory-system atherosclerosis
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the-circulatory-system blood-clotting
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diet-and-health cardiovascular-disease
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diet-and-health interpreting-data-on-risk-factors
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genes-and-health as28 主题
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gas-exchange-cell-membranes-and-transport properties-of-gas-exchange-surfaces
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gas-exchange-cell-membranes-and-transport ficks-law-of-diffusion
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gas-exchange-cell-membranes-and-transport the-mammalian-lung
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gas-exchange-cell-membranes-and-transport cell-membranes
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gas-exchange-cell-membranes-and-transport practical-investigating-membrane-permeability
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gas-exchange-cell-membranes-and-transport diffusion-and-facilitated-diffusion
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gas-exchange-cell-membranes-and-transport active-transport
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gas-exchange-cell-membranes-and-transport osmosis
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nucleic-acids nucleotides-and-phosphodiester-bonds
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nucleic-acids dna-structure
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nucleic-acids rna-structure
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proteins transcription
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proteins translation
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proteins nature-of-the-genetic-code
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proteins amino-acids-and-peptide-bonds
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proteins levels-of-protein-structure
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proteins globular-proteins-structure-and-function
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proteins fibrous-proteins-structure-and-function
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proteins the-role-of-enzymes
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proteins mode-of-enzyme-action
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proteins enzyme-and-substrate-concentrations
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inheritance dna-replication
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inheritance mutations
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inheritance inheritance-key-terms
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inheritance pedigree-diagrams
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inheritance monohybrid-crosses
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inheritance chi-squared-test
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inheritance genetic-screening
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gas-exchange-cell-membranes-and-transport properties-of-gas-exchange-surfaces
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voice-of-the-genome as19 主题
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cell-structure-and-organisation cell-theory
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cell-structure-and-organisation eukaryotic-cells
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cell-structure-and-organisation prokaryotic-cells
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cell-structure-and-organisation organisation-of-cells
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cell-structure-and-organisation microscopy
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cell-structure-and-organisation magnification-calculations
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cell-structure-and-organisation recognising-organelles
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cell-division the-cell-cycle
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cell-division mitosis
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cell-division practical-identifying-mitosis-in-plant-cells
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reproduction-and-inheritance mammalian-gametes
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reproduction-and-inheritance fertilisation-in-mammals
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reproduction-and-inheritance genes-and-linkage
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reproduction-and-inheritance meiosis-source-of-genetic-variation
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differentiation-and-variation stem-cells
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differentiation-and-variation stem-cells-in-medicine
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differentiation-and-variation cell-differentiation
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differentiation-and-variation epigenetics
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differentiation-and-variation phenotypes-and-variation
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cell-structure-and-organisation cell-theory
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biodiversity-and-natural-resources as19 主题
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biodiversity the-variety-of-life
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biodiversity measuring-biodiversity-within-a-habitat
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biodiversity comparing-biodiversity-between-habitats
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biodiversity ecological-niches-and-adaptations
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biodiversity natural-selection
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biodiversity hardy-weinberg-equation
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biodiversity reproductive-isolation
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biodiversity classification
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biodiversity conservation-of-biodiversity
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resources-from-plants plant-cell-structure
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resources-from-plants plant-stems
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resources-from-plants importance-of-water-and-inorganic-ions-to-plants
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resources-from-plants starch-and-cellulose-structure-and-function
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resources-from-plants plant-fibres
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resources-from-plants practical-identifying-tissue-types-within-stems
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resources-from-plants tensile-strength-plant-fibres
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resources-from-plants development-of-drug-testing
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resources-from-plants antimicrobial-properties-of-plants
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resources-from-plants sustainability-and-plant-materials
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biodiversity the-variety-of-life
proteins translation
Exam code:8BN0
Translation
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Translation occurs in the cytoplasm of the cell
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After leaving the nucleus via a nuclear pore, the mRNA molecule attaches to a ribosome
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In the cytoplasm there are free molecules of tRNA (transfer RNA)
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tRNA is a single stranded molecule of RNA that folds into a clover-like structre
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tRNA molecules have a triplet of unpaired bases at one end, known as the anticodon, and a region at the other end where a specific amino acid can attach
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There are about 20 different tRNA molecules, each with a specific anticodon and specific amino acid binding site
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The tRNA molecules bind with their specific amino acids (also in the cytoplasm) and bring them to the mRNA molecule on the ribosome
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The triplet of bases (anticodon) on each tRNA molecule pairs with a complementary triplet on the mRNA molecule called the codon
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Near the beginning of the mRNA is a triplet of bases called the start codon (AUG)
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This is a signal to start off translation
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AUG codes for an amino acid called methionine
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Two tRNA molecules fit onto the ribosome at any one time, bringing the amino acid they are each carrying side by side
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A peptide bond is then formed, via a condensation reaction, between the two amino acids
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This process continues until a ‘stop’ codon on the mRNA molecule is reached – this acts as a signal for translation to stop and at this point the amino acid chain coded for by the mRNA molecule is complete
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The amino acid chain then forms the final polypeptide


The process of translation
Examiner Tips and Tricks
Make sure you learn both stages of protein synthesis fully. Don’t forget – transcription occurs in the nucleus but translation occurs in the cytoplasm!
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