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Biology AS CIE

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  1. 1-cell-structure
    10 主题
  2. 2-biological-molecules
    19 主题
  3. 3-enzymes
    13 主题
  4. 4-cell-membranes-and-transport
    16 主题
  5. 5-the-mitotic-cell-cycle
    8 主题
  6. 6-nucleic-acids-and-protein-synthesis
    9 主题
  7. 7-transport-in-plants
    11 主题
  8. 8-transport-in-mammals
    16 主题
  9. 9-gas-exchange
    6 主题
  10. 10-infectious-diseases
    6 主题
  11. 11-immunity
    10 主题
课 4, 主题 9
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4-2-movement-into-and-out-of-cells AS endocytosis-and-exocytosis

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Exam code:9700

Endocytosis & exocytosis

  • The processes of diffusion, osmosis and active transport are responsible for the transport of individual molecules or ions across cell membranes

  • However, the bulk transport of larger volumes of materials into or out of cells is also possible

  • Examples of these larger quantities of materials that might need to cross the membrane include:

    • Large molecules such as proteins or polysaccharides

    • Parts of cells

    • Whole cells e.g., bacteria

  • Bulk transport into cells = endocytosis

  • Bulk transport out of cells = exocytosis

    • These two processes require energy input and are therefore forms of active transport

Endocytosis

  • Endocytosis is the process by which the cell surface membrane folds inwards and engulfs material, forming a small sac (or ‘endocytic vesicle’) around it

  • There are two forms of endocytosis:

    • Phagocytosis:

      • This is the bulk intake of solid material by a cell

      • Cells that specialise in this process are called phagocytes

      • The vacuoles formed are called phagocytic vacuoles

      • An example is the engulfing of bacteria by phagocytic white blood cells

    • Pinocytosis:

      • This is the bulk intake of liquids

Diagram illustrating phagocytosis: a bacterium is engulfed by a white blood cell, digested in a vacuole, and undigested remains expelled.
The process of phagocytosis of a bacterium by a phagocyte (white blood cell)

Exocytosis

  • Exocytosis is the process by which materials are removed from, or transported out of, cells (the reverse of endocytosis)

  • The substances to be released (such as enzymes or hormones) are packaged into secretory vesicles formed from the Golgi body

  • These vesicles then travel to the cell surface membrane

  • Here they fuse with the cell membrane and release their contents outside of the cell

  • An example is the secretion of digestive enzymes from pancreatic cells

Diagram illustrating exocytosis with labels: Golgi body, secretory vesicles, cell membrane, and product release. Arrows show vesicle fusion and product release.
The process of exocytosis

Examiner Tips and Tricks

Remember – active transport, endocytosis and exocytosis all require the input of energy. This energy is provided by the hydrolysis of ATP produced during respiration.

To get the mark in the exam you have to specifically state ‘exocytosis‘ for bulk transport out of the cell and ‘endocytosis‘ for bulk transport into the cell. Simply stating ‘bulk transport’ is not specific enough, the examiner will want to know what type of bulk transport and for this you need to state the scientific name!

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