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  1. 1-biological-molecules

    1-1-biological-molecules-carbohydrates
    11 主题
  2. 1-2-biological-molecules-lipids
    3 主题
  3. 1-3-biological-molecules-proteins
    5 主题
  4. 1-4-proteins-enzymes
    12 主题
  5. 1-5-nucleic-acids-structure-and-dna-replication
    8 主题
  6. 1-6-atp-water-and-inorganic-ions
    4 主题
  7. 2-cell-structure
    2-1-cell-structure
    7 主题
  8. 2-2-the-microscope-in-cell-studies
    4 主题
  9. 2-3-cell-division-in-eukaryotic-and-prokaryotic-cells
    8 主题
  10. 2-4-cell-membranes-and-transport
    7 主题
  11. 2-5-cell-recognition-and-the-immune-system
    7 主题
  12. 2-6-vaccines-disease-and-monoclonal-antibodies
    6 主题
  13. 3-exchange-and-transport
    3-1-adaptations-for-gas-exchange
    6 主题
  14. 3-2-human-gas-exchange
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  15. 3-3-digestion-and-absorption
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  16. 3-4-mass-transport-in-animals
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  17. 3-5-the-circulatory-system-in-animals
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  18. 3-6-mass-transport-in-plants
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  19. 4-genetics-variation-and-interdependence
    4-1-dna-genes-and-chromosomes
    7 主题
  20. 4-2-dna-and-protein-synthesis
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  21. 4-3-genetic-diversity-mutations-and-meiosis
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  22. 4-4-genetic-diversity-and-adaptation
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  23. 4-5-species-and-taxonomy
    4 主题
  24. 4-6-biodiversity
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  25. 5-energy-transfers-in-and-between-organisms-a-level-only
    5-1-photosynthesis-a-level-only
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  26. 5-2-respiration-a-level-only
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  27. 5-3-energy-and-ecosystems-a-level-only
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  28. 5-4-nutrient-cycles-a-level-only
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  29. 6-organisms-respond-to-changes-in-their-environments-a-level-only
    6-1-response-to-stimuli-a-level-only
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  30. 6-2-nervous-coordination-a-level-only
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  31. 6-3-skeletal-muscles-a-level-only
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  32. 6-4-homeostasis-a-level-only
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  33. 7-genetics-populations-evolution-and-ecosystems-a-level-only
    7-1-inheritance-a-level-only
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  34. 7-2-populations-a-level-only
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  35. 7-3-evolution-a-level-only
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  36. 7-4-populations-in-ecosystems-a-level-only
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  37. 8-the-control-of-gene-expression-a-level-only
    8-1-genetic-mutations-a-level-only
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  38. 8-2-regulation-of-gene-expression-a-level-only
    11 主题
  39. 8-3-using-genome-projects-a-level-only
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  40. 8-4-gene-technologies-a-level-only
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  41. exam-guidance-and-skills
    essay-guidance
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Myogenic stimulation of the heart

  • The contraction of heart muscle is myogenic; this means that the heart beats at a baseline rate without any input from the nervous system

  • Thy myogenic control of the heart beat involves the:

    • sinoatrial node (SAN): a group of cells in the wall of the right atrium, often referred to as the pacemaker

    • atrioventricular node (AVN): conductive tissue that links the atria and ventricles

    • bundle of His: conductive fibres that carry waves of depolarisation down the septum to the base of the ventricles

    • Purkyne tissue: conductive fibres that carry waves of depolarisation from the base of the ventricles into the ventricle walls

  • The sequence of events during which the heart beat is initiated and controlled is as follows:

Event

Effect on heart

The SAN initiates a wave of depolarisation which passes across the atria

The atria contract

The wave of depolarisation reaches non-conducting tissue that separates the atria and ventricles, before it passes to the AVN

There is a delay which allows the atria to empty into the ventricles before ventricular contraction begins

Electrical activity passes from the bundle of His to the Purkyne tissue

The ventricles contract from the base upwards

Diagram of a heart showing the depolarisation pathway: sinoatrial node, atrioventricular node, bundle of His and Purkyne fibres
The wave of depolarisation spreads across the heart from the SAN in a coordinated manner

Examiner Tips and Tricks

Make sure that you don’t confuse the SAN and the AVN:

  • The SAN initiates the heart beat

  • The AVN conducts electrical activity from the atria to the ventricles