Biology_A-level_Aqa
-
1-biological-molecules
1-1-biological-molecules-carbohydrates11 主题-
1-1-1-biological-molecules-key-terms
-
1-1-2-biological-molecules-reactions
-
1-1-3-monosaccharides
-
1-1-4-glucose
-
1-1-5-the-glycosidic-bond
-
1-1-6-chromatography-monosaccharides
-
1-1-7-disaccharides
-
1-1-8-starch-and-glycogen
-
1-1-9-cellulose
-
1-1-10-biochemical-tests-sugars-and-starch
-
1-1-11-finding-the-concentration-of-glucose
-
1-1-1-biological-molecules-key-terms
-
1-2-biological-molecules-lipids3 主题
-
1-3-biological-molecules-proteins5 主题
-
1-4-proteins-enzymes12 主题
-
1-4-1-many-proteins-are-enzymes
-
1-4-2-enzyme-specificity
-
1-4-3-how-enzymes-work
-
1-4-4-required-practical-measuring-enzyme-activity
-
1-4-5-drawing-a-graph-for-enzyme-rate-experiments
-
1-4-6-using-a-tangent-to-find-initial-rate-of-reaction
-
1-4-7-limiting-factors-affecting-enzymes-temperature
-
1-4-8-limiting-factors-affecting-enzymes-ph
-
1-4-10-limiting-factors-affecting-enzymes-enzyme-concentration
-
1-4-11-limiting-factors-affecting-enzymes-substrate-concentration
-
1-4-12-limiting-factors-affecting-enzymes-inhibitors
-
1-4-14-control-of-variables-and-uncertainty
-
1-4-1-many-proteins-are-enzymes
-
1-5-nucleic-acids-structure-and-dna-replication8 主题
-
1-5-2-nucleotide-structure-and-the-phosphodiester-bond
-
1-5-3-dna-structure-and-function
-
1-5-4-rna-structure-and-function
-
1-5-5-ribosomes
-
1-5-6-the-origins-of-research-on-the-genetic-code
-
1-5-8-the-process-of-semi-conservative-replication
-
1-5-9-calculating-the-frequency-of-nucleotide-bases
-
1-5-10-the-watson-crick-model
-
1-5-2-nucleotide-structure-and-the-phosphodiester-bond
-
1-6-atp-water-and-inorganic-ions4 主题
-
2-cell-structure2-1-cell-structure7 主题
-
2-2-the-microscope-in-cell-studies4 主题
-
2-3-cell-division-in-eukaryotic-and-prokaryotic-cells8 主题
-
2-4-cell-membranes-and-transport7 主题
-
2-5-cell-recognition-and-the-immune-system7 主题
-
2-6-vaccines-disease-and-monoclonal-antibodies6 主题
-
3-exchange-and-transport3-1-adaptations-for-gas-exchange6 主题
-
3-2-human-gas-exchange10 主题
-
3-2-1-the-human-gas-exchange-system
-
3-2-2-dissecting-the-gas-exchange-system
-
3-2-3-microscopy-and-gas-exchange-surfaces
-
3-2-4-investigating-gas-exchange
-
3-2-5-the-alveolar-epithelium
-
3-2-6-ventilation-and-gas-exchange
-
3-2-8-the-effects-of-lung-disease
-
3-2-9-pollution-and-smoking-data
-
3-2-10-risk-factor-data
-
3-2-11-correlations-and-causal-relationships
-
3-2-1-the-human-gas-exchange-system
-
3-3-digestion-and-absorption5 主题
-
3-4-mass-transport-in-animals6 主题
-
3-5-the-circulatory-system-in-animals8 主题
-
3-6-mass-transport-in-plants6 主题
-
4-genetics-variation-and-interdependence4-1-dna-genes-and-chromosomes7 主题
-
4-2-dna-and-protein-synthesis6 主题
-
4-3-genetic-diversity-mutations-and-meiosis7 主题
-
4-4-genetic-diversity-and-adaptation6 主题
-
4-5-species-and-taxonomy4 主题
-
4-6-biodiversity9 主题
-
5-energy-transfers-in-and-between-organisms-a-level-only5-1-photosynthesis-a-level-only5 主题
-
5-2-respiration-a-level-only7 主题
-
5-3-energy-and-ecosystems-a-level-only9 主题
-
5-4-nutrient-cycles-a-level-only4 主题
-
6-organisms-respond-to-changes-in-their-environments-a-level-only6-1-response-to-stimuli-a-level-only12 主题
-
6-1-1-survival-and-response
-
6-1-2-growth-factors-in-flowering-plants
-
6-1-3-indoleacetic-acid-iaa
-
6-1-4-taxes-and-kinesis
-
6-1-5-reflex-arcs
-
6-1-6-required-practical-investigating-animal-movement
-
6-1-7-the-pacinian-corpuscle
-
6-1-8-pacinian-corpuscles-generator-potential
-
6-1-9-investigating-touch-and-temperature-receptors
-
6-1-10-the-human-retina
-
6-1-11-myogenic-stimulation-of-the-heart
-
6-1-13-heart-rate
-
6-1-1-survival-and-response
-
6-2-nervous-coordination-a-level-only10 主题
-
6-3-skeletal-muscles-a-level-only6 主题
-
6-4-homeostasis-a-level-only11 主题
-
6-4-1-principles-of-homeostasis
-
6-4-2-negative-feedback
-
6-4-3-glucose-concentration-and-insulin
-
6-4-4-glucose-regulation-glucagon
-
6-4-5-glucose-regulation-adrenaline
-
6-4-6-glucose-regulation-the-liver
-
6-4-7-diabetes
-
6-4-8-required-practical-determining-the-concentration-of-glucose-in-urine
-
6-4-9-nephron-structure
-
6-4-10-nephron-function
-
6-4-11-control-of-blood-water-potential
-
6-4-1-principles-of-homeostasis
-
7-genetics-populations-evolution-and-ecosystems-a-level-only7-1-inheritance-a-level-only6 主题
-
7-2-populations-a-level-only3 主题
-
7-3-evolution-a-level-only5 主题
-
7-4-populations-in-ecosystems-a-level-only7 主题
-
8-the-control-of-gene-expression-a-level-only8-1-genetic-mutations-a-level-only2 主题
-
8-2-regulation-of-gene-expression-a-level-only11 主题
-
8-2-1-totipotent-cells
-
8-2-2-stem-cells
-
8-2-3-the-use-of-stem-cells
-
8-2-4-producing-tissue-cultures-of-explants
-
8-2-5-regulation-of-transcription
-
8-2-6-evaluating-data-about-genetic-expression
-
8-2-7-epigenetics
-
8-2-8-epigenetics-and-disease
-
8-2-9-rna-interference
-
8-2-10-two-types-of-tumours
-
8-2-11-tumour-development
-
8-2-1-totipotent-cells
-
8-3-using-genome-projects-a-level-only4 主题
-
8-4-gene-technologies-a-level-only13 主题
-
8-4-1-recombinant-dna-technology
-
8-4-2-producing-fragments-of-dna
-
8-4-3-investigating-the-specificity-of-restriction-enzymes
-
8-4-4-polymerase-chain-reaction
-
8-4-5-culture-of-transformed-host-cells
-
8-4-6-uses-of-recombinant-dna-technology
-
8-4-7-dna-probes-and-dna-hybridisation
-
8-4-8-screening-patients
-
8-4-9-genetic-counselling-and-personalised-medicine
-
8-4-10-variable-number-tandem-repeats
-
8-4-11-gel-electrophoresis
-
8-4-12-genetic-fingerprinting
-
8-4-13-uses-of-genetic-fingerprinting
-
8-4-1-recombinant-dna-technology
-
exam-guidance-and-skillsessay-guidance3 主题
6-1-9-investigating-touch-and-temperature-receptors
Investigating touch and temperature receptors in skin
-
It is possible to investigate receptors in human skin, e.g.:
-
sensitivity of temperature receptors
-
habituation of touch receptors
-
resolution of touch receptors
-
Investigating the sensitivity of temperature receptors in human skin
Apparatus
-
A thermometer
-
A water bath at 45 °C
-
A bowl of iced water
-
A willing human subject
Method
-
Take a thermometer from a water bath kept at 45 °C and wipe it dry with a paper towel
-
Touch the thermometer on the back of the subject’s hand in different places
-
For each touch, record:
-
the temperature on the thermometer
-
whether the subject feels warmth, or whether only touch can be felt
-
-
Repeat steps 1-3 using the thermometer kept in iced water
Results and analysis
-
The results should show that the temperature receptors on the skin can only detect temperature when it deviates significantly from body temperature; when the thermometer reaches a temperature that is close to body temperature then only touch will be felt
Limitations
-
This experiment relies on humans relaying information about sensations they are experiencing; the subject may convince themselves that they can feel warmth or cold when they don’t
-
The results are subjective
-
Only one subject is used
-
Ideally, this experiment would be repeated using a number of different subjects in order to achieve more reliable results
-
Investigating habituation of touch receptors in human skin
-
Over time touch receptors in the skin can become habituated to certain stimuli; this means that response to a stimulus decreases after repeated or prolonged exposure
-
E.g. individuals usually become unaware of the clothing they are wearing after a period of time
-
Method
-
Select a human subject and ensure they are seated comfortably with their eyes covered
-
Covering the eyes prevents sight of the stimulus from influencing perceived touch
-
-
Use a soft, standardised stimulus, such as a cotton bud, soft brush, or piece of thread
-
Start a stopwatch and then gently apply the stimulus to the same spot, e.g. the back of the hand or forearm; the stimulus could be applied:
-
at regular intervals, e.g. once every 2 seconds
-
as steady, light pressure
-
-
Ask the subject to observe any point at which they can no longer feel the stimulus; this is evidence of habituation
-
Record the time at which the subject no longer perceives the stimulus
-
After a rest period of 1–2 minutes, repeat the procedure to observe whether the sensitivity returns
-
Repeat with multiple volunteers and test different areas of skin, e.g. back of neck, palm, forearm, to compare results
Limitations
-
Maintaining the same intensity of touch for a long period of time can be difficult; a machine is usually required
-
There is likely to be a large variation in the results if multiple subjects are use; recent studies have revealed that habituation to touch differs widely between individuals
Investigating resolution of touch receptors in human skin
-
The number of touch receptors present affects the resolution of the skin, i.e. the ability to distinguish between two different points of contact
-
Areas with high resolution have a large number of touch receptors so they are able to identify two points of contact even if they are extremely close together
-
Apparatus
-
Blunt pair of scissors, or an unfolded paperclip
-
Die
-
Ruler
-
A human subject
Method
-
Open scissors or paperclip to a measured distance, e.g. 4 cm
-
Use a ruler to confirm the exact spacing
-
-
Ensure that the subject is seated comfortably with their eyes covered
-
Randomly apply either one point or two points simultaneously to the same area of the skin, e.g. forearm
-
Pressure should be gentle and even
-
Randomness can be achieved by throwing a die and applying one point for an odd number and two points for an even number
-
-
Ask the subject to report whether they felt one or two points
-
Record the number of points applied and whether or not the subject’s response was correct in a results table
-
Repeat steps 3-5 at least twice more at the same distance
-
Reduce the distance between the points and repeat steps 3-6
-
Continue adjusting the distance until you determine the minimum distance at which the subject can correctly identify two points
-
Repeat the procedure on a different area of the body, e.g. fingertip, back of hand, or neck

Results and analysis
-
Areas such as the fingers and soles of the feet tend to have a much higher resolution
-
Two points of contact can be identified by a subject when the points are very close together
-
-
Areas such as the back of the hands and legs tend to have lower resolution
Limitations
-
This experiment relies on humans relaying information, so there is a chance of human error
-
Only one subject is used
-
Ideally, this experiment would be repeated using a number of different subjects in order to achieve more reliable results
-