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  1. 1-biological-molecules

    1-1-biological-molecules-carbohydrates
    11 主题
  2. 1-2-biological-molecules-lipids
    3 主题
  3. 1-3-biological-molecules-proteins
    5 主题
  4. 1-4-proteins-enzymes
    12 主题
  5. 1-5-nucleic-acids-structure-and-dna-replication
    8 主题
  6. 1-6-atp-water-and-inorganic-ions
    4 主题
  7. 2-cell-structure
    2-1-cell-structure
    7 主题
  8. 2-2-the-microscope-in-cell-studies
    4 主题
  9. 2-3-cell-division-in-eukaryotic-and-prokaryotic-cells
    8 主题
  10. 2-4-cell-membranes-and-transport
    7 主题
  11. 2-5-cell-recognition-and-the-immune-system
    7 主题
  12. 2-6-vaccines-disease-and-monoclonal-antibodies
    6 主题
  13. 3-exchange-and-transport
    3-1-adaptations-for-gas-exchange
    6 主题
  14. 3-2-human-gas-exchange
    10 主题
  15. 3-3-digestion-and-absorption
    5 主题
  16. 3-4-mass-transport-in-animals
    6 主题
  17. 3-5-the-circulatory-system-in-animals
    8 主题
  18. 3-6-mass-transport-in-plants
    6 主题
  19. 4-genetics-variation-and-interdependence
    4-1-dna-genes-and-chromosomes
    7 主题
  20. 4-2-dna-and-protein-synthesis
    6 主题
  21. 4-3-genetic-diversity-mutations-and-meiosis
    7 主题
  22. 4-4-genetic-diversity-and-adaptation
    6 主题
  23. 4-5-species-and-taxonomy
    4 主题
  24. 4-6-biodiversity
    9 主题
  25. 5-energy-transfers-in-and-between-organisms-a-level-only
    5-1-photosynthesis-a-level-only
    5 主题
  26. 5-2-respiration-a-level-only
    7 主题
  27. 5-3-energy-and-ecosystems-a-level-only
    9 主题
  28. 5-4-nutrient-cycles-a-level-only
    4 主题
  29. 6-organisms-respond-to-changes-in-their-environments-a-level-only
    6-1-response-to-stimuli-a-level-only
    12 主题
  30. 6-2-nervous-coordination-a-level-only
    10 主题
  31. 6-3-skeletal-muscles-a-level-only
    6 主题
  32. 6-4-homeostasis-a-level-only
    11 主题
  33. 7-genetics-populations-evolution-and-ecosystems-a-level-only
    7-1-inheritance-a-level-only
    6 主题
  34. 7-2-populations-a-level-only
    3 主题
  35. 7-3-evolution-a-level-only
    5 主题
  36. 7-4-populations-in-ecosystems-a-level-only
    7 主题
  37. 8-the-control-of-gene-expression-a-level-only
    8-1-genetic-mutations-a-level-only
    2 主题
  38. 8-2-regulation-of-gene-expression-a-level-only
    11 主题
  39. 8-3-using-genome-projects-a-level-only
    4 主题
  40. 8-4-gene-technologies-a-level-only
    13 主题
  41. exam-guidance-and-skills
    essay-guidance
    3 主题
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Uncontrolled cell division & cancer

  • Mitosis is normally a controlled process

  • Cancer results from uncontrolled mitosis, forming a tumour (an abnormal mass of cells)

  • Mutations in genes controlling the cell cycle (e.g. oncogenes, tumour suppressor genes) can lead to this loss of control

    • These mutations may

      • cause continuous cell division

      • prevent programmed cell death (apoptosis)

Cancer treatments

  • Most cancer treatments aim to slow or stop mitosis in rapidly dividing cells

  • Some examples include

    • Methotrexate: a drug which inhibits DNA nucleotide synthesis

    • Taxol: a drug which prevents disassembly of spindle fibres (freezing mitosis)

Examiner Tips and Tricks

Whilst you are not required to know specific examples of cancer treatment drugs, it is common for exam questions to provide information about a drug with an expectation that you can apply your knowledge of the cell cycle to explain how they work.

Note also that you will study uncontrolled cell division and cancer in more detail when you reach Unit 8: The Control of Gene Expression.